Summary: It has been clear for a long time that after transplantation of a lymphoid organ, hematopoietic stem cells can regenerate the compartments of the organ, provided that the rest of its architecture - the strome, the epithelia and the vessels - is intact. Ahead lies the even greater challenge to assemble also these other architectural elements of a lymphoid organ by transplanting stem cells. The workshop on lymphoid organogenesis was convened to review current knowledge of and experimental skills involved in this grand project to build a lymphoid organ from its individual cellular components.
Author(s): Alt, K. W.; Rösing, F. W.; Teschler-Nicola, M., (Eds.): ISBN: 3-211-82974-1 Publisher:
Price: $82.00
Summary: The study of teeth is an important key to the biology and culture of past and living populations. Due to their extreme hardness, their numerous and highly heritable characteristics and their susceptibility to environmental responses teeth allow inferences of human evolution, adaptation, living conditions, environments, group affinity, kinship and the life and death of single persons. This has been gradually discovered during the last thirty years, and it lead to the formation of the new field of dental anthropology. It is rooted in biology and has strong ties to dentistry, forensics and the humanities. This book gives a comprehensive view of this new field of dental anthropology. It provides a basic introduction as well as a reference for the specialist in anthropology, forensics, ecology, paleontology and dentistry. Most aspects are completely new, particularly the syntheses. The basic experience and literature is of a broad international and multilingual origin.
Summary: The advances in human genetics that have ocurred during the past 20 years have revolutionized our knowledge of the role played by inheritance in health and disase. It is clear that our DNA determines not only the emergence of catastrophic single-gene disorders, which affect millions of persons worldwide, but also interacts with environments to predispose individuals to cancer, allergy, hypertension, heart disease, diabetes, psychiatric disorders and even to some infectious diseases. Overall, the study of longevity and the demonstration of genes favouring a long lifespan suggest that such protective systems exist. In recent years, the study of genetic polymorphisms has made clear that some alleles have beneficial effects. These discoveries can substantially improve our understanding of the interactions between genetics and the environment, between pathogenetic mechanisms and new treatments.
Summary: RNA Motifs and Regulatory Elements is the new edition of the successful book, "Regulatory RNA". It alerts the reader to the importance of regulatory RNA elements for the many different areas of cellular life.
The computational and experimental methods and tools to search for new interesting regulatory RNA structures are explained and compared. The knowledge on regulatory RNA structures and elements already available is concisely summarized as well as catalogued. In addition, interesting RNA elements are analyzed in detail regarding their dynamics, regulation, and as a dominant topic of current resarch in molecular biology, including areas such as RNA mediated regulation of gene-expression, DNA/RNA chip data, and ribozymes, splicing, or telomerases in aging. Medical implications are also covered. Future progress and research are finally outlined.
Author(s): Day, I. N.M., (Ed.): ISBN: 3-540-41388-X Publisher:
Price: $95.00
Summary: This volume describes high-throughput approaches to a series of robust, established methodologies in molecular genetic studies of population samples. Such developments have been essential not only to linkage and association studies of single-gene and complex traits in humans, animals and plants, but also to the characterisation of clone banks, for example in mapping of genomes. Chapters have been written by developers or highly experienced end-users concerned with a diverse array of biological applications. The book should appeal to any researcher for whom costs and throughput in their genetics laboratory have become an issue.
